Let me say, at this point, that if I’m left alone to take Nebivolol at the dose I’ve worked out for myself, and which has proven is effective and safe, I’m fine – but the medical profession insists on fucking up my life, either through incompetence (Arrowe Park Hospital), or through, as is the case here, penny-pinching with a complete and utter disregard for patient safety.
I have diarrhoea again!
As you might know, I’ve had this problems since Christmas, along with a bout of vomiting I put down to a Norovirus infection for lack of any other apparent reason.
As I mentioned at the time, I suspected my beta-blocker, Nebivolol, was giving me grief, including the diarrhoea, so I reduced it to the absolute minimum, 0.625mg every 12 hours (more effective than 1.25mg once a day, as I metabolise this drug very quickly).
The diarrhoea went away, and I felt fine (relatively speaking), and my BP and heart rate were fine too. On the current dose, 1,25mg every 12 hours, my heart rate is 10-12bpm lower (mid to high 60s, not harmful but not happy about it either), and my BP is 128/64 – effectively unchanged (previously 127/63)
However, my numbnuts GP, as I mentioned, in order to save a few coppers, has prescribed 5mg tablets instead of 2.5mg, and these are quite impossible to cut into eighths to get the right dose.** As a result, I’ve taken 1.25mg every 12 hours for a couple of days, and now I have diarrhoea again.
**Even though they’re scored in quarters, the tablets are very hard and brittle, and almost impossible to cut accurately, even in quarters, as they tend to either shatter or break along fault lines caused by stresses imposed in the manufacturing process (most tablets are compressed powder, held together with a binder, in an extremely low-tech process).
There can, therefore, be no doubt that Nebivolol is the cause,** even though I suspect the Norovirus (or whatever), caused me to become sensitised to it. The increased dose has also buggered my breathing again. In addition, I’ve also felt desperately ill again since starting the higher dose, which also confirms what I thought previously – Nebivolol, except at a very low dose, is making me much sicker than I need be, and that is not acceptable.
** There’s also a remote possibility that I have mysteriously developed an intolerance to dairy produce, as in recent weeks both Clover, once, and cheese, twice, have resulted in diarrhoea, and last night, in need of an easy meal, I had cheese and crackers – so that’s 3 out of 3 for dairy. Hmm… (Yep, I realise it could be the fat content, but as fried food causes no problems, I think that’s unlikely.)
So as soon as I’ve finished this, I’m faxing my idiot GP telling him that being forced to take a higher dose in the interests of saving, quite literally, a few coppers, is not acceptable. (The dairy problem is a different issue – Nebivolol at the dose I’m now forced to take causes a whole raft of problems as I’ve mentioned previously.)