Increasing my Zomorph from 100mg to 130mg b.d. (in 10mg steps due to the risk of catastrophic respiratory failure if I hit the full 30mg increase all at once), has resulted in much more pain, not less. This, to my surprise, is not entirely unknown, though the research was relatively recently published on January 6, 2013.
Anyway, those of you who, like me, are dependent upon morphine for the treatment of severe, intransigent, pain, might be interested to learn that instead of making you feel better it can make you a hell of a lot worse.
It might, of course, be some time before it results in a fix for the problem, but it can’t hurt to make your doctors aware that you know about it and will be keeping an eye on developments. This is where we, the patients, have an edge over our doctors as we – those of us unable to work, anyway, and have computers – have more time to keep an eye on the research fraternity than they do.
I’m due to start the full 130mg dose tonight. Whether this will change things, for good or ill, I have no idea right now. The weird thing is, though, that increasing the dose of Zomorph in the past, and initially this time too, has made Oramorph more effective. It still is, it’s just that I have far more pain without it that I had previously, which is unfortunate as my GP expects my Oramorph use to fall.
On the current showing, that simply is not going to happen.
Update: For the second morning in succession I managed to get back to sleep after taking my 06.00 meds. Only for another hour, but better than nothing.